Development of new inhaled nicotine delivery method, and associated pharmacokinetics, for neuroimaging studies of smoking
Scanner-safe instrumentation provides highly-controlled administration of nicotine for addiction studies of ad libitum smoking.
To investigate nicotine addiction in clincial settings used fMRI, we developed a tool that can control precisely the pharmacokinetics of nicotine. See:
Mujica-Parodi LR, Amgalan A, Nedic S, Wenke M, Lithen A, Benveniste H, Makaryus R, Govindarajan S, Strey HH. Development of an MRI-Compatible Nasal Drug Delivery Method for Probing Nicotine Addiction Dynamics.
