Laboratory for Computational Neurodiagnostics

What is LCNeuro?

Control systems engineering approach to homeostatic regulation of brain circuits.

Models are mechanistic, multi-scale, and generative.

Modulation of circuit dynamics in neuropsychiatric disorders
and therapeutics.

Research Intersections

Clinical Neuroscience

Leveraging advanced neuroimaging to research neurological and psychiatric disorders.

Basic Neuroscience

Probing fundamental mechanisms: metabolism, neural-glial regulation, firing, and conduction.

Computational Neuroscience

Quantifying control circuit regulation across neural scales and physiological systems.

Instrumentation Development

Developing hardware and software solutions for state-of-the-art neuroimaging.

Analytics Method Development

Accelerating discovery with Scientific Machine Learning.

Our Articles In

Featured Publications

Basic Neuroscience

Clinical Neuroscience

Computational Neuroscience

Analytics Method Development

Biomimetic Model of Corticostriatal Micro-Assemblies Discovers a Neural Code

Nature Communications

•

2025

Clinical Neuroscience

Brain Aging Shows Nonlinear Transitions, Suggesting a Midlife "Critical Window" for Metabolic Intervention

Proceedings of the National Academy of Sciences of the USA

•

2025

Computational Neuroscience

Analytics Method Development

Achieving Occam's Razor: Deep Learning for Optimal Model Reduction

PLoS Computational Biology

•

2024

Selected Press

Invisibilia — Fear (Interview with Lulu Miller)

National Public Radio

•

January 1, 2015

Low-carb diet may reverse age-related brain deterioration, study finds

•

March 7, 2020

Interview with Ken Ford & Dawn Kernagis

STEM-Talk Podcast

•

October 28, 2020

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